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THE ROLE OF INTRATHECAL ANALGESIA IN PALLIATIVE CARE. Karen Overmeyer,
MSN, APRN, BC, and Jill Laird, MSN, APRN, Virginia Commonwealth University
health Systems, Richmond, VA.
Today, even in the hands of expert pain practitioners, approximately 14%
of patients with cancer suffer from intractable cancer pain. While increased
opioids and adjunct medications often help, side effects from these interventions
may become intolerable. Oncology nurses are in a unique position to evaluate
and identify patients who require special intervention.
Recently in multicenter randomized clinical trials, we studied the use
of intrathecal drug delivery systems and found this option to offer significant
benefits to this population of patients. The results of this clinical
trail will be reviewed discussing its implication, as well as other potential
invasive techniques. The unique benefits, including statistically significant
cost effectiveness, and potential complications of this analgesic technique
will be explored.
A total of 202 patients with intractable pain were randomized to receive
implantable drug delivery systems.
A review of selected candidates for this invasive procedure will be described
to include screening tools and techniques used to ensure appropriate candidates
are benefited and ongoing post-placement evaluation discussed. The main
outcome measure was pain control combined with change of toxicity as measured
by NCI’s common toxicity criteria.
Long-term management techniques and potential complications will be described,
including problem-solving techniques. Systems issues to ensure appropriate
management of patients will be reviewed. Case studies and other treatment
options will be explored for candidates requiring other interventions.
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